Integrated network pharmacology analysis and experimental validation to investigate the mechanism of flavan-3-ols and aromatic resins in depression

HIGHLIGHTS

• What: The authors showed that bioactive compounds flavan-3-ols and aromatic resin targeted 281 common genes related to depression.
• Who: Posted Date October et al. from the (UNIVERSITY) have published the research: Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Flavan-3-ols and Aromatic resin in Depression, in the Journal: (JOURNAL)
• How: Analyses of results showed that Epigallocatechin gallate shown the most active compound showing highest affinity with binding_energy - 7.3 kcal/mol towards serotonin 1A (5HT1A) -7.4 kcal/mol towards D2 -8.9 kcal/mol . . .
  

   

  

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