HIGHLIGHTS
- who: Diego F. Gauto from the CEA s of Health, South Drive, MSC, Bethesda, MD, USAGoethe University have published the Article: Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Because this approach is limited to methyl groups, no information about the backbone conformation can be obtained, which excludes any de novo structure determination. The authors show that the NMR/EM approach provides near-atomic-resolution structures even if only moderateresolution EM data are available, an often-encountered situation that prohibits . . .
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