Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment

HIGHLIGHTS

• who: Alice Moussy and colleagues from the Ecole Pratique des Hautes Etudes, PSL Research University, UMRS, INSERM, Univ-Evry, Evry, CNRS, Université, France have published the research work: Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment, in the Journal: (JOURNAL) of December/21,/2016
• what: The authors show that major transcriptional changes leading to a multilineage-primed gene expression state occur very rapidly during the first cell cycle. The authors show that each cell explores (at its own pace and independently of cell . . .
  

   

  

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