Integrated transcriptomic analysis reveals immune signatures distinguishing persistent versus resolving outcomes in mrsa bacteremia

HIGHLIGHTS

  • What: Modules associated with host DNMT3A genotype Prior studies by the group performed on a subset of patients included in this study demonstrated that a gain-in-function mutation in DNA methyltransferase 3A (DNMT3A; heterozygous A C B T_cell signaling pathways distinguish persistent from resolving MRSA bacteremia. The authors examined the transcriptome, DNMT3A genotype and IL-10 proteome of whole peripheral blood to differentiate immune_response pathways associated with RB versus PB outcomes in clinical MRSA bacteremia.
  • Who: Alice Prince and colleagues from the Columbia University, United States have published the Article: Integrated transcriptomic analysis reveals . . .

     

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