Integrating crispr/cas systems with programmable dna nanostructures for delivery and beyond

HIGHLIGHTS

  • who: Petteri Piskunen from the Materials, Department of Bioproducts and Biosystems, Aalto University, , Aalto, Finland have published the article: Integrating CRISPR/Cas systems with programmable DNA nanostructures for delivery and beyond, in the Journal: (JOURNAL) of June/17,/2022
  • what: Although the authors focus on DNA-based applications, it is noteworthy to mention that RNA nanotechnology also allows for programmable strand-displacement schemes that can be used to conditionally activate CRISPR functions (Oesinghaus and Simmel, 2019; Lin et_al, 2020).

SUMMARY

    Cas13 (formerly C2c2) cleaves a ssRNA target rather than DNA (Abudayyeh . . .

     

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