Integrating evolutionary and regulatory information with multispecies approach implicates genes and pathways in obsessive-compulsive disorder

HIGHLIGHTS

• who: Hyun Ji Noh from the (UNIVERSITY) have published the paper: Integrating evolutionary and regulatory information with multispecies approach implicates genes and pathways in obsessive-compulsive disorder, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report a new strategy that overcomes limitations of less comprehensive candidate gene studies and exome-only approaches, and identifies functional variants associated with increased risk of OCD. For primary analyses, the authors focused on 41,504 "high-confidence" SNPs detected by both, with highly correlated allele frequencies (AF) (Pearson's ρ=0.999, p and amp;lt; 2.2 . . .
  

   

  

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