Integration of epigenetic mechanisms into non-genotoxic carcinogenicity hazard assessment: focus on dna methylation and histone modifications

HIGHLIGHTS

  • who: Daniel Desaulniers and collaborators from the AL: B, Ottawa, K A , Canada have published the paper: Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications, in the Journal: (JOURNAL)
  • what: The working definition of epigenetics utilised for the purpose of this work is "the study of molecular processes Int.

SUMMARY

    Epigenetic programing is fundamental for normal mammalian development and provides a mechanism by which the environment can rapidly alter gene_expression within single or multiple generations. Constitutive heterochromatin is associated with H3K9me3 that . . .

     

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