Integration of machine learning methods to dissect genetically imputed transcriptomic profiles in alzheimer’s disease

HIGHLIGHTS

  • who: Carlo Maj from the University of Marburg, Germany have published the paper: Integration of Machine Learning Methods to Dissect Genetically Imputed Transcriptomic Profiles in Alzheimeru2019s Disease, in the Journal: (JOURNAL)
  • what: The authors investigate the applicability of different machine_learning methods on omics data using, as a case study, matrices of tissue-specific predicted transcriptomic profiles in Alzheimer`s disease (AD). The aim of the unsupervised analysis was to identify the up or down-regulation of certain genes in specific tissue types in cases and healthy samples. The aim of the cross-tissue analysis was . . .

     

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