HIGHLIGHTS
- who: Hongyu Li and colleagues from the Germany University Medical Center HamburgEppendorf, Germany have published the research work: Integration of metabolomics and transcriptomics provides insights into enhanced osteogenesis in Ano5Cys360Tyr knock-in mouse model, in the Journal: (JOURNAL) of 06/Dec/2022
- what: In the present study, RNA-seq and metabolomics analyses were used to explore differentially expressed genes and intracellular metabolites of mature mouse calvarial osteoblasts (mCOBs) after 14-day osteogenic cultures from Ano5Cys360Tyr compared with Ano5+/ + mice, and the underlying metabolic pathways were predicted followed by verification with functional experiments.
- how . . .
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