Integrative analysis of eqtl and gwas summary statistics reveals transcriptomic alteration in alzheimer brains

HIGHLIGHTS

  • who: Pradeep Varathan from the (UNIVERSITY) have published the Article: Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains, in the Journal: (JOURNAL)
  • what: We performed an integrative analysis of AD GWAS and brain eQTL summary statistics to estimate the potential transcriptomic changes inside AD brains.
  • how: For a more detailed analysis of the intronic variants the authors used the SNP Nexus online tool .
  • future: Efforts to explore new merging methods for integrative analysis and trans-eQTL effects are warranted in the future work.
 

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