Integrative analysis of high-throughput rnai screen data identifies the fer and crkl tyrosine kinases as new regulators of the mitogenic erk-dependent pathways in transformed cells

HIGHLIGHTS

• who: INSERM UMR and colleagues from the Université Rennes, SFR Biosit, Rennes, France have published the article: Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells, in the Journal: (JOURNAL)
• what: The authors propose a small interfering RNA genetic screen and an integrative approach to identify kinase networks involved in the proliferation of cancer cells. Identification of FER and CRKL as pivotal protein_kinases involved in mitogenic signaling pathways While CRKL (CRK-like) and FER non-receptor tyrosine . . .
  

   

  

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