Integrative analysis of iso-seq and rna-seq reveals dynamic changes of alternative promoter, alternative splicing and alternative polyadenylation during angiotensin ii-induced senescence in rat primary aortic endothelial cells

HIGHLIGHTS

• who: . et al. from the Hong Kong Polytechnic University, Hong Kong SAR, China have published the research work: Integrative analysis of Iso-Seq and RNA-seq reveals dynamic changes of alternative promoter, alternative splicing and alternative polyadenylation during Angiotensin II-induced senescence in rat primary aortic endothelial cells, in the Journal: (JOURNAL)
• what: The authors systematically characterized the transcriptome diversity and changes in RAECs before and after Ang II treatment.
• how: The authors identified alternative promoters (APs) by considering both promoter expression and promoter activity. The authors identified 1109 genes with multiple promoters . . .
  

   

  

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