Integrative analysis of summary data from gwas and eqtl studies implicates genes differentially expressed in alzheimer’s disease

HIGHLIGHTS

  • who: Brian Lee from the , have published the Article: Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimeru2019s disease, in the Journal: (JOURNAL)
  • what: Through this analytical technique, the authors aim to identify novel genes that are differentially expressed in AD, which may help reveal the biological pathway from genetic determinants to transcriptomic features to phenotypic outcomes and help disease modeling and therapeutic target discovery. The authors provide the effect plots in Figs 5, 6, and 7. The authors provide a brief discussion on the three novel findings . . .

     

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