Integrative analysis of transcriptome and metabolome to illuminate the protective effects of didymin against acute hepatic injury

HIGHLIGHTS

  • who: Lijun Pang et al. from the Guangxi Medical University, Nanning, China have published the article: Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury, in the Journal: Mediators of Inflammation of 12/01/2023
  • what: Based on the multiomics analysis this study is aimed at investigating the underlying mechanism of didymin against acute liver injury (ALI). This study shows that didymin can ameliorate LPS/D-Gal-induced ALI by inhibiting the glycerophospholipid metabolism and PI3K/Akt and TLR4/NF-u03baB pathways. As a part of the . . .

     

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