HIGHLIGHTS
SUMMARY
The overexpression of WDR12 demonstrated that the knockdown of WDR12 promoted apoptosis and inhibited the proliferation of tumor cells (Li et_al, 2020a). Hepatocellular carcinoma was another type of tumor that experienced up-regulated expression of WDR12 where the knockdown of WDR12 expression resulted in reduced proliferation and migration of HepG2 and Huh-7 cells (Li et_al, 2020b). The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO), have been constructed as a result of the fast development of whole genome sequencing technology (Blum et_al, 2018; Hutter and Zenklusen, 2018). WDR12 transcript is largely expressed . . .
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