Integrative cell type-specific multi-omics approaches reveal impaired programs of glial cell differentiation in mouse culture models of dm1

HIGHLIGHTS

  • who: Mário Gomes-Pereira from the National University of, University of Rochester, United States have published the paper: Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1, in the Journal: (JOURNAL)
  • what: Given the pronounced splicing dysregulation in DMSXL astrocytes, the authors focused the subsequent analyses on this glial cell type.
  • how: The authors used this technique to compare the transcriptome of primary neurons OPC OL and astrocytes isolated from DMSXL mice with those collected from WT controls. The authors calculated . . .

     

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