Integrin mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through nadph oxidase-nlrp3 inflammasome axis-dependent microglial activation

HIGHLIGHTS

• who: Liyan Hou from the All experiments involving animals were conducted according to the ethical policies and their care were approved by the Institutional Animal Care and Use Committee of Dalian Medical University, China have published the paper: Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase-NLRP3 inflammasome axis-dependent microglial activation, in the Journal: (JOURNAL)
• what: To differentiate the contribution of NOX sub-members in Mac1-regulated activation of NLRP3 inflammasome, specific siRNAs were used to silence NOX1 and NOX2, two main members of NOX family . . .
  

   

  

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