Interaction, cooperative promoter modulation, and renal colocalization of gcma and pitx2*

HIGHLIGHTS

  • who: Steffen W. Schubert from the (UNIVERSITY) have published the research: Interaction, Cooperative Promoter Modulation, and Renal Colocalization of GCMa and Pitx2*, in the Journal: (JOURNAL) of April/26,/2004
  • what: The authors show that Pitx proteins interact via their conserved homeodomain with the DNA-binding domain of GCMa.

SUMMARY

    The authors identify Pitx transcription factors as GCMa-interacting proteins. Most of the GCMa was released from the ternary complex and re-appeared in a binary complex with the labeled probe (Fig 6c). Transactivation assays were performed using a reporter containing . . .

     

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