Interaction of arginine-rich cell-penetrating peptides with an artificial neuronal membrane

HIGHLIGHTS

  • who: Piotr Mucha and colleagues from the Laboratory of Chemistry of Biologically Active Compounds, Faculty of Chemistry, University of Gdanu0301sk, Gdansk, Poland have published the Article: Interaction of Arginine-Rich Cell-Penetrating Peptides with an Artificial Neuronal Membrane, in the Journal: Cells 2022, 1638 of 12/05/2022
  • what: The authors applied circular dichroism (CD) spectroscopy and coarse-grained molecular dynamics (CG MD) simulations to investigate the interactions of two RRCPPs Tat(49-57)-NH2 (arginine-rich motif of Tat HIV-1 protein) and PTD4 (a less basic Ala-scan analog of the Tat peptide . . .

     

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