Interaction of lats1 with smac links the mst2/hippo pathway with apoptosis in an iap-dependent manner

HIGHLIGHTS

• who: Lucu00eda Garcu00eda-Gutiu00e9rrez from the (UNIVERSITY) have published the article: Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner, in the Journal: (JOURNAL) of 29/03/2022
• what: The authors show that the restoration of LATS1 proapoptotic signalling in combination with SMs can restore the sensitivity of melanoma cells to apoptosis. The analysis showed that the SMAC interactors regulated by LATS1WT overexpression were grouped in five clusters, which Cell Death and Disease 13:692 include the well-known interactors of the IAP family including XIAP, C . . .
  

   

  

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