Interaction of the european genotype porcine reproductive and respiratory syndrome virus (prrsv) with sialoadhesin (cd169/siglec-1) inhibits alveolar macrophage phagocytosis

HIGHLIGHTS

  • who: Miet I De Baere and collaborators from the (UNIVERSITY) have published the research work: Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis, in the Journal: (JOURNAL)
  • what: This study examined whether interaction of European genotype PRRSV with primary alveolar macrophages (PAM) affects their phagocytic capacity. This study shows that European genotype PRRSV inhibits PAM phagocytosis in vitro through the interaction with its internalization receptor Sn. The analysis shows that both the percentage of macrophages phagocytosing beads , are downregulated. Using inactivated PRRSV . . .

     

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