Interaction of the la-related protein slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mrnas

HIGHLIGHTS

  • who: Manchester and colleagues from the Division of Molecular and Cellular Function, School of Biological Sciences, The University of, PT, UK have published the Article: Interaction of the La-related protein Slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mRNAs, in the Journal: (JOURNAL)
  • what: The authors propose that Slf1 is a ribosome-associated translational modulator that stabilises stalled/collided ribosomes prevents ribosome frameshifting and so promotes translation of a set of highly-translated mRNAs that together facilitate cell survival and adaptation to stress. The authors focused most of the following described analyses . . .

     

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