Interactions between avibactam and ceftazidime-hydrolyzing class d -lactamases

HIGHLIGHTS

  • who: Jean-Marie Fru00e8re and colleagues from the National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-Negative Bacteria have published the research: Interactions between Avibactam and Ceftazidime-Hydrolyzing Class D -Lactamases, in the Journal: (JOURNAL)
  • what: The authors determine the kinetic parameters of the hydrolysis of ceftazidime by OXA-163 and OXA-427 and show that these two enzymes are reasonably well inactivated by avibactam, a result that might be of clinical significance. Avibactam is often administered in combination with and 300 M knowledge, no analyses of the interactions between avibactam and ceftazidime . . .

     

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