Interactome analysis of bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

HIGHLIGHTS

  • who: Nisan Denizce Can and collaborators from the Department of Molecular Biology-Genetics and Biotechnology, Istanbul Technical University, Istanbul, Genetic and Metabolic Diseases Research and Investigation Center, Marmara University, Istanbul, Turkey have published the paper: Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation, in the Journal: PLOS ONE of 11/08/2021
  • what: Altogether, the authors propose that Bag-1S negatively regulates VCP activity and ERAD (Fig 7D). The authors characterized the isoform-specific interactomes of Bag-1 and identified novel interacting partners. The authors propose that Bag . . .

     

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