HIGHLIGHTS
- who: Top from the Department of Pathology and Medical Biology, Division of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands have published the paper: Interferon gamma peptidomimetic targeted to interstitial, in the Journal: (JOURNAL)
- what: The authors demonstrate pronounced antifibrotic effects of targeted IFNu03b3 peptidomimetic to PDGFu03b2R-expressing cells without identifiable systemic Oncotarget Figure 3: Fibroferon reduces u03b1-SMA expression in mouse UUO kidneys. a. The authors propose that mimu03b3-BiPPB binds to the PDGFu03b2R and following internalization, the construct is able to interact with the intracellular part of IFNu03b3R1 and initiates . . .
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