Interferon inducible porcine 2′, 5′-oligoadenylate synthetase-like protein limits porcine reproductive and respiratory syndrome virus infection via the mda5-mediated interferon- signaling pathway

HIGHLIGHTS

  • who: ' et al. from the Foshan University https://orcidorg/0000-0002-6589, have published the paper: Interferon Inducible Porcine 2′, 5′-oligoadenylate Synthetase-Like Protein Limits Porcine Reproductive and Respiratory Syndrome Virus Infection via the MDA5-Mediated Interferon- Signaling Pathway, in the Journal: (JOURNAL)
  • what: The authors report that pOASL participates in MDA5-mediated IFN signal pathway. The authors demonstrate that pOASL is a new restriction factor which dampens PRRSV infection via MDA5-mediated type I IFN signaling.
  • how: The authors evaluated the effect of pOASL on PRRSV replication in_vitro and attempted to . . .

     

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