Interferon regulatory factor 1 (irf-1) promotes intestinal group 3 innate lymphoid responses during citrobacter rodentium infection

HIGHLIGHTS

• who: Angelika Schmalzl from the Animals and housing conditions Irf1-/- mice, were kindly provided by AKru00f6ger (University of Magdeburg). Irf1-/- mice were bred with Irf1+/- as littermate controls or were co-housed with Irf1+/+ mice for at least four weeks to ensure adaptation of the intestinal microbiome. No evident differences in u03b1 and u03b2diversity of the intestinal microbiota could be detected by , based metagenomic sequencing (Supplementary Fig. A, B). Ifng-/- mice were originally purchased from the Jackson Laboratory and were bred inhouse. Irf1fl/fl mice were generated in-house through crossing a mouse strain purchased from the . . .
  

   

  

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