Interleukin-17a mediates hippocampal damage and aberrant neurogenesis contributing to epilepsy-associated anxiety

HIGHLIGHTS

  • who: Kyung-Ok Cho from the Department of Pharmacology, College of Medicine, The Catholic University of Korea, Seoul, South Korea, Department (PSU), United States have published the paper: Interleukin-17A Mediates Hippocampal Damage and Aberrant Neurogenesis Contributing to Epilepsy-Associated Anxiety, in the Journal: (JOURNAL)
  • what: The authors investigated the role of IL-17A in epilepsy-associated anxiety and its biological mechanisms, using IL-17A wildtype (WT) and IL-17A knockout (KO) mice subjected to pilocarpine-induced status epilepticus (SE). The epileptic IL-17A KO mice in this study showed a reduction in hilar EGCs . . .

     

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