Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: biological role in induction, regulation, and treatment

HIGHLIGHTS

  • who: Stella Amarachi Ihim and colleagues from the University of Illinois at Chicago, United States have published the research work: Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment, in the Journal: (JOURNAL)

SUMMARY

    It acts on T helper 1 (Th1) cells, macrophages, Natural killer (NK) cells, natural killer T (NKT) cells, B cells, dendritic cells (DCs), and even nonpolarized T_cells to produce interferon gamma (IFN-g) in the presence of IL-12. Other cell types which are capable of producing IFN-g via the synergistic action . . .

     

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