Interleukin-23 mediates osteoclastogenesis in collagen-induced arthritis by modulating microrna-223

HIGHLIGHTS

  • who: Shih-Yao Chen and collaborators from the Department of Nursing, College of Nursing, Hwa University of Technology, Tainan, Taiwan have published the research: Interleukin-23 Mediates Osteoclastogenesis in Collagen-Induced Arthritis by Modulating MicroRNA-223, in the Journal: (JOURNAL)
  • what: The aim of this study was to examine the association between IL-23 and miR-223 in contributing to osteoclastogenesis and arthritis. This hypothesis was proved by the experiments showing reduced osteoclastogenesis in the miR-223 sponge and STAT4-specific shRNA-treated BMMs upon stimulating with IL-23 . The authors proved and proposed a . . .

     

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