Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance

HIGHLIGHTS

  • who: Shamma Almuraikhy from the School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK have published the article: Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance, in the Journal: (JOURNAL)
  • what: The aims of the study were to test two hypotheses: the adipogenic capacity of SC pre-adipocyte is abrogated in all IR individuals compared with IS individuals; this lesion is accompanied by greater release of IL-6 by pre-adipocytes that directly inhibits adipogenesis. This study provides data that supports previous findings of elevated IL-6 expression . . .

     

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