HIGHLIGHTS
- who: Apelin et al. from the School of Medicine, China Medical University, Taichung, Taiwan have published the paper: International Publisher, in the Journal: (JOURNAL)
- what: In this study, analyses of metastatic and nonmetastatic osteosarcoma tissue samples from the TCGA database revealed higher levels of APLN and PLOD2 expres- MST1/MOB1 signaling is involved in APLNinduced increases of PLOD2-mediated migration of osteosarcoma cells Recent studies have reported that several signaling pathways (including the PI3K/Akt/mTOR, NF-u03baB, JAK/STAT, Hippo and hypoxia pathways) have an important role in cancer metastasis, including osteosarcoma . The study . . .
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