Interrelation between -cardiac actin treadmilling and myocardin-related transcription factor-a nuclear shuttling in cardiomyocytes

HIGHLIGHTS

  • who: Mark-Alexander Gorey and collaborators from the Institut de Biologie Paris-Seine (IBPS), CNRS, ERL, Biological Adaptation and have published the research: Interrelation between -Cardiac Actin Treadmilling and Myocardin-Related Transcription Factor-A Nuclear Shuttling in Cardiomyocytes, in the Journal: (JOURNAL)
  • what: In the present study, by using an MRTFA-GFP fused protein produced by a recombinant adenovirus and the time-lapse live cell imaging, the nucleocytoplasmic shuttle kinetics of MRTFA and actin dynamics were analyzed in primary cultures of neonatal rat cardiomyocytes. This experiment shows that MRTFA nucleocytoplasmic shuttling is fast after serum . . .

     

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