HIGHLIGHTS
SUMMARY
Perinatal complications and pregnancy outcomes, as well as an unfavorable neonatal prognosis, are often associated with "major obstetric syndromes", in particular preeclampsia (PE) and fetal growth restriction (FGR). This definition covers a wide range of highly reactive oxygen-containing compounds, including free_radicals (e_g, superoxide, hydroxyl and peroxyl radicals) and secondary products of radical reactions-non-radical compounds (e_g, hydrogen peroxide, singlet oxygen, peroxynitrite, lipid hydroperoxide, hypochlorite anion, and ozone). MiR-127-3p is considered a molecular switch in macrophage polarization, therefore, its key role in the pathogenesis of diseases associated with inflammation and immune_response . . .
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