Intervention time decides the status of autophagy, nlrp3 activity and apoptosis in macrophages induced by ox‐ldl

HIGHLIGHTS

  • who: Liang Zheng from the Laboratory of Department of Surgery, the First Affiliated Hospital of Sun YatSen University, Guangzhou, Guangdong, China have published the article: Intervention time decides the status of autophagy, NLRP3 activity and apoptosis in macrophages induced by oxu2010LDL, in the Journal: (JOURNAL)
  • what: The results from this study showed that NLRP3 expression was significantly reduced when oxLDL phagocytosis was blocked in the early stage. This work has revealed that treatments for lipid disorders at an early stage may help maintain macrophage autophagic status, inhibit inflammatory reactions, and reduce macrophage apoptosis and foam . . .

     

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