Intestinal region-specific wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

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  • who: Ronja S. Adam from the Laboratory for Experimental Oncology and Radiobiology (LEXOR), Amsterdam University Medical Centers, Meibergdreef, AZ Amsterdam, The Netherlands have published the research: Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development, in the Journal: (JOURNAL)
  • what: The authors propose that the longitudinal or craniocaudal axis in the intestine is an attractive model to study how the characteristics of cancer initiating cells influence the transformation process, using the confined variation of regional differentiation in the same organ. Because small intestinal cancer is very . . .

     

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