Intestinal stem cells damaged by deoxycholic acid via ahr pathway contributes to mucosal barrier dysfunction in high-fat feeding mice

HIGHLIGHTS

  • who: Leheng Liu and colleagues from the Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the research: Intestinal Stem Cells Damaged by Deoxycholic Acid via AHR Pathway Contributes to Mucosal Barrier Dysfunction in High-Fat Feeding Mice, in the Journal: (JOURNAL)
  • what: Several studies have linked HFD to decreased AHR signalling, which is an important reason for the impairment of intestinal barrier function as well as the development of metabolic syndrome . The study showed that, unlike its long-term effects, a two-week high-fat feeding . . .

     

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