HIGHLIGHTS
- who: Zhanhai Yin from the University of Liu00e8ge, Belgium United States have published the research: Intra-articular injection of clioquinol ameliorates osteoarthritis in a rabbit model, in the Journal: (JOURNAL)
- what: The authors attempt to explore new autophagy-inducing pharmacophores. The authors investigated the effects of clioquinol on autophagy process in chondrocytes. The study shows that intra-articular injection of clioquinol can distinctly repress articular cartilage erosion and rescue the proteoglycan content.
- how: Together these results indicated that clioquinol exposure could facilitate autophagy in human OA chondrocytes. to rescue the IL-1u00df-induced . . .
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