HIGHLIGHTS
- who: Louis Jolivet and collaborators from the 301, CNRS, Universitu00e9 d`Orlu00e9ans, Rue Charles Sadron, Orlu00e9ans, France have published the article: Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment-Drug Conjugates (FDCs), in the Journal: Pharmaceutics 2022, 1524 of 22/07/2022
- what: The aims of this approach are to reduce systemic toxicity while enhancing antitumor efficacy. Although it was not the goal of this study, it is noteworthy to add that the average DAR was probably improvable by_(i) a slightly better reduction for S4 and S3, to . . .
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