Intra-tumoral cd8+ t-cell infiltration and pd-l1 positivity in homologous recombination deficient pancreatic ductal adenocarcinoma

HIGHLIGHTS

• who: Bryn Golesworthy from the Autonomous University of Madrid, Spain have published the article: Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma, in the Journal: (JOURNAL)
• what: While CD8+Tlymphocytes are adjacent to tumor cells in the microenvironment of melanoma tumors, the CD8+T-lymphocyte infiltrate in PDAC study, the authors show increased intra-tumoral CD8+ T-lymphocyte infiltration and PD-L1 positivity by immunohistochemistry, corroborating previously reported transcriptomic evidence for T-cell inflammation in HR-d PDAC . The authors demonstrate that HR-d PDAC exhibits . . .
  

   

  

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