Intracellular a β 42 aggregation leads to cellular thermogenesis

HIGHLIGHTS

• who: Chyi Wei Chung et al. from the (UNIVERSITY) have published the research: Intracellular A u03b2 42 Aggregation Leads to Cellular Thermogenesis, in the Journal: (JOURNAL) of May/26,/2022
• what: The authors show that aggregation and heat retention by Au03b2 peptides are favored under intracellular-mimicking ionic conditions which could potentially promote thermogenesis. The authors show here that the presence of Au03b242 in live HEK293T_cells leads to an average temperature increase, in addition to 10035 https://doi.org/10.1021/jacs.2c03599 J. Am. Lastly, using classical molecular dynamics simulations on Au03b2, the authors . . .
  

   

  

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