HIGHLIGHTS
- who: T. H. Rabbitts from the Institute of Cancer Research, Division of Cancer Therapeutics, Cotswold Road, Sutton, London , NG, UK have published the research: Intracellular Antibodies for Drug Discovery and as Drugsof the Future, in the Journal: Antibodies 2023, 2023, 12, 12, xx FOR FOR PEER PEER REVIEW REVIEW Antibodies of /2023/
- what: Iterations of this approach have been developed in which direct fusion of various E3 ligases with intracellular antibody fragments (biodegraders) creates a binary complex in cells to lead to ubiquitination of target proteins and their proteosome degradation .
- how: The first . . .
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