Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy

HIGHLIGHTS

• who: Qingyuan Feng from the State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China have published the paper: Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy, in the Journal: (JOURNAL)
• what: The authors aimed to exploit intracellular components that may interact with ADI and figure out whether these interactions are lethal. Cellular autophagy induced by ADI expressed in the cytosol Cellular autophagy was detected because nutrient starvation is the major reason to trigger excessive autophagy . The authors aimed at understanding whether . . .
  

   

  

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