HIGHLIGHTS
- who: Nirakar Sahoo from the DepartmentSchiller University have published the research work: Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1, in the Journal: Scientific Reports Scientific Reports
- how: Data were analyzed with FitMaster (HEKA Elektronik) FITMASTER NEXT (Multi Channel Systems MCS GmbH Reutlingen Germany) and IgorPro software (WaveMetrics Lake Oswego OR).
SUMMARY
To assess the sensitivity of Kv10.1 channels to intracellular hemin or heme, the authors expressed the channel-coding mRNA in Xenopus oocytes and recorded voltage-dependent currents in membrane patches large enough . . .
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