HIGHLIGHTS
- who: Zhen Xing from the State Key Laboratory of Pharmaceutical Biotechnology, School of Life, Nanjing University, Xianlin Nanjing, China have published the article: Intracellular mRNA phase separation induced by cationic polymers for tumor immunotherapy, in the Journal: (JOURNAL)
- what: The authors report that cationic polymers (CPs) have strong RNA LLPS-inducing activity. To validate this, in the present study, the authors investigated three types of cationic polymers with the cytoplasmic condensates of RNA both in_vitro and in_vivo, with particular emphasis on the encapsulated mRNA in the process. The authors demonstrated that encapsulating mRNA transcripts via . . .
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