HIGHLIGHTS
- who: Celeste Rizzello from the Istituto Nazionale Tumori, Via Venezian, Milan, Italy have published the article: Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling, in the Journal: (JOURNAL)
- what: The authors demonstrate that in u00adFaslpr/lpr mice the intracellular form of osteopontin (iOPN) is protective against the development of B cell lymphomas. The authors show the intracellular form in autoimmune splenic B cells, accumulated as dots surrounding the peri-nuclear region. Complementing the previous findings on the development of a CD5 + B cell malignancy in absence of SPARC , the authors . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.