Intracellular survival of streptococcus pneumoniae in human alveolar macrophages is augmented with hiv infection

HIGHLIGHTS

  • who: Tinashe K. Nyazika from the Liverpool School of Tropical Medicine in the UK (ProtocolUniversity of KwaZulu-Natal have published the paper: Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection, in the Journal: (JOURNAL)
  • what: Using ex vivo and in_vivo infection, the authors show that AM from PLHIV exhibit poor intracellular killing of pneumococci and demonstrated a role of intracellular survival in continued propagation of infection. Using both ex vivo and in_vivo approaches, the study demonstrates that pneumococci survive intracellularly in human AMs, and that this is more frequent . . .

     

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