HIGHLIGHTS
- who: Barth D. Grantu00a7 et al. from the Rutgers University, Piscataway, NJ , USA have published the paper: Intracellular trafficking, in the Journal: (JOURNAL)
SUMMARY
There are several endocytic pathways that utilize different mechanisms to internalize portions of the plasma_membrane. In early endosomes some ligand-receptor complexes dissociate due to the reduced pH of the endosomal lumen. Many receptors then recycle to the plasma_membrane either directly or indirectly via recycling endosomes. The best studied of the general endocytosis regulators identified in this screen are RME-1 and RME-8 (Grant and Hirsh, 1999; Zhang . . .
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