Intracellular zinc protects kv7 k+ channels from ca2+/calmodulin-mediated inhibition

HIGHLIGHTS

• who: Xinhe Yang from the C (5% CO2) and passaged about every , daysRat dorsal root ganglion neurons were isolated and cultured as described before (63). All animal experiments were performed in accordance with the Animal Care and Ethical Committee of Hebei Medical University (approval number: IACUC-Hebmu-2020007). CHO cells were transfected with human , (Y15065) or , (NM_004519) cDNA subcloned into pCDNA3., (Youbio), with or without WT CaM (NP_008819.1) or Ca, (a gift from Dr Zhiqiang Yan, Fudan University). Point mutations in , and , were produced by Youbio. YFP-tubby (tubby-R, cYFP was a gift from Andrew . . .
  

   

  

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