HIGHLIGHTS
- who: Qiwei Qian from the Bologna, (IRCCS), Italy University of Milano-Bicocca, Italy have published the paper: Intrahepatic activated leukocyte cell adhesion molecule induces CD6highCD4+ T cell infiltration in autoimmune hepatitis, in the Journal: (JOURNAL)
SUMMARY
The authors also compared the phenotypes between CD6high and CD6low subsets within intrahepatic CD4+ T_cells isolated from AIH and HC. The effect of ALCAM on T_cell migration was investigated in_vitro. Perturbations of both peripheral and intrahepatic T_cells have been observed in AIH development, which is characterized by defective regulatory T_cells and expansion of pathogenic cytotoxic T_cells. There . . .
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